ESTIMATING THE FITNESS COST AND BENEFIT OF CEFIXIME RESISTANCE IN NEISSERIA GONORRHOEAE TO INFORM PRESCRIPTION POLICY: A MODELLING STUDY.

Estimating the fitness cost and benefit of cefixime resistance in Neisseria gonorrhoeae to inform prescription policy: A modelling study.

BackgroundGonorrhoea is one of the most common bacterial sexually transmitted infections in England.Over Corner Chair 41,000 cases were recorded in 2015, more than half of which occurred in men who have sex with men (MSM).As the bacterium has developed resistance to each first-line antibiotic in turn, we need an improved understanding of fitness be

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p53 mutation and deletion contribute to tumor immune evasion

TP53 (or p53) is widely accepted to be a tumor suppressor.Upon various cellular stresses, p53 mediates cell cycle arrest and apoptosis to maintain genomic stability.p53 is also discovered to suppress tumor growth through regulating metabolism and ferroptosis.However, p53 is always lost or mutated in human and the loss or mutation of p53 is related

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Stages of change and self-efficacy are related to consumption of food markers among Brazilian adolescents and young adults

ObjectiveThis study aimed at analyzing the association between stages of change, consumption of food markers, and self-efficacy in the adoption of healthy eating practices, adjusted by nutritional knowledge, among Brazilian adolescents and young adults.MethodsA cross-sectional analysis was conducted with 347 individuals from schools in the Federal

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Studying the effect of tissue-specific expression of the K1 gene encoding LysM-receptor-like kinase on the development of symbiosis in peas

To study the role of pea LysM receptor-like kinase K1 in the coordination of the infection process, starting in epidermis and nodule organogenesis Upper PCA Board in the root cortex of plants, during the development of rhizobium-legume symbiosis, the genetic constructs in which K1 gene was cloned under the control of tissue-specific promoter pLeEXT

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